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Eggs, embryos and the evolution of imprinting: insights from the platypus genome

29 Oct 2009

Abstract excerpt

Genomic imprinting is widespread in eutherian and marsupial mammals. Although there have been many hypotheses to explain why genomic imprinting evolved in mammals, few have examined how it arose. The host defence hypothesis suggests that imprinting evolved from existing mechanisms within the cell that act to silence foreign DNA elements that insert into the genome. However, the changes to the mammalian genome...

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Share to Epigenetics and DNA Methylation
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Share to Prenatal Screening and Diagnostics

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PMID: 19874717
DOI: 10.1071/rd09092

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