Article
Poly(ADP-ribose) polymerase-1 (PARP-1) longer alleles spanning the promoter region may confer protection to bilateral Meniere's disease.
Acta oto-laryngologica - 1 Nov 2009
Lopez-Escamez Jose A, Moreno Antonia, Bernal Monica, Perez-Garrigues Herminio, Santos-Perez Sofia, Soto-Varela Andres, Aran Ismael, Fernandez-Sanfrancisco Omar, Lopez-Nevot Alicia, Lopez-Nevot Miguel A
Abstract excerpt
CONCLUSION: The longer alleles (CA)17-20 of the promoter region of PARP-1 gene may confer some protection against bilateral Meniere's disease (BMD). OBJECTIVE: To analyze microsatellite (CA)(n) polymorphisms in the promoter region of PARP-1 gene and seek out risk and protective variants for BMD....
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