Article
Polymorphisms in genes encoding aquaporins 4 and 5 and estrogen receptor α in patients with Ménière's disease and sudden sensorineural hearing loss.
Life sciences - 21 Mar 2013
Nishio Naoki, Teranishi Masaaki, Uchida Yasue, Sugiura Saiko, Ando Fujiko, Shimokata Hiroshi, Sone Michihiko, Otake Hironao, Kato Ken, Yoshida Tadao, Tagaya Mitsuhiko, Hibi Tatsuya, Nakashima Tsutomu
Abstract excerpt
AIMS: The etiologies of Ménière's disease and idiopathic sudden sensorineural hearing loss (SSNHL) remain unclear. The homeostasis of the water and blood circulation in the inner ear is essential for maintaining its hearing and equilibrium functions, and aquaporins and estrogen are involved in the fluid or ion balance in the inner ear. We investigated the associations between genetic polymorphisms in aquaporin 4...
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