Article
The genetic basis of long QT and short QT syndromes: a mutation update.
Human mutation - 1 Nov 2009
Hedley Paula L, Jørgensen Poul, Schlamowitz Sarah, Wangari Romilda, Moolman-Smook Johanna, Brink Paul A, Kanters Jørgen K, Corfield Valerie A, Christiansen Michael
Abstract excerpt
Long QT and short QT syndromes (LQTS and SQTS) are cardiac repolarization abnormalities that are characterized by length perturbations of the QT interval as measured on electrocardiogram (ECG). Prolonged QT interval and a propensity for ventricular tachycardia of the torsades de pointes (TdP) type are characteristic of LQTS, while SQTS is characterized by shortened QT interval with tall peaked T-waves and a...
Topics
- A Kinase Anchor Proteins
- Ankyrins
- Arrhythmias, Cardiac
- Calcium-Binding Proteins
- Caveolin 3
- Cytoskeletal Proteins
- Genotype
- Humans
- Ion Channels
- Long QT Syndrome
- Membrane Proteins