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Article

Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators.

Journal of medicinal chemistry - 26 Nov 2009

Schlienger Nathalie, Lund Birgitte W, Pawlas Jan, Badalassi Fabrizio, Bertozzi Fabio, Lewinsky Rasmus, Fejzic Alma, Thygesen Mikkel B, Tabatabaei Ali, Bradley Stefania Risso, Gardell Luis R, Piu Fabrice, Olsson Roger

Abstract excerpt

Herein we describe the discovery of ACP-105 (1), a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. Compound 1 was developed from a series of compounds found in a HTS screen using the receptor s...

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Identifiers

PMID: 19856921
DOI: 10.1021/jm901149c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19856921-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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