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Article

Cisplatin ototoxicity and protection: clinical and experimental studies.

The Tohoku journal of experimental medicine - 1 Nov 2009

Rybak Leonard P, Mukherjea Debashree, Jajoo Sarvesh, Ramkumar Vickram

Abstract excerpt

Cisplatin is a chemotherapeutic agent that is widely used to treat a variety of malignant tumors. Serious dose-limiting side effects like ototoxicity, nephrotoxicity and neurotoxicity occur with the use of this agent. This review summarizes recent important clinical and experimental investigations of cisplatin ototoxicity. It also discusses the utility of protective agents employed in patients and in experimental...

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Identifiers

PMID: 19851045
DOI: 10.1620/tjem.219.177
PMCID: PMC2927105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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