Article
FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma.
The British journal of dermatology - 1 May 2010
Venza I, Visalli M, Tripodo B, De Grazia G, Loddo S, Teti D, Venza M
Abstract excerpt
BACKGROUND: Several cancer-related genes are silenced by promoter hypermethylation in skin cancers. However, to date the somatic epigenetic events that occur in cutaneous squamous cell carcinoma (SCC) tumorigenesis have not been well defined. OBJECTIVES: To examine epigenetic abnormalities of FOXE1, a gene located on chromosome 9q22, a region frequently lost in SCC. METHODS: We investigated the methylation status...
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