Article
[Ser49gly polymorphism as predictor of development of hereditary sick sinus node syndrome].
Kardiologiia - 1 Jan 2009
Nikulina S Iu, Shul'man V A, Chernova A A, Voevoda M I, Maksimov V N, Kazarinova Iu L
Abstract excerpt
We demonstrated for the first time on clinico-genetic material an association of hereditary sick sinus node syndrome (SSNS) with polymorphism of beta-adrenorecetor gene. We found that heterozygous variant of Ser49gly of beta-adrenoreceptor gene was significantly more often met in patients with SSNS and their healthy relatives than in subjects of control group. In the group of patients with SSNS contrary to...
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