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Article

DNA packaging by lambda-like bacteriophages: mutations broadening the packaging specificity of terminase, the lambda-packaging enzyme.

Genetics - 1 Jan 2010

Feiss Michael, Reynolds Erin, Schrock Morgan, Sippy Jean

Abstract excerpt

The DNA-packaging specificities of phages lambda and 21 depend on the specific DNA interactions of the small terminase subunits, which have support helix-turn-recognition helix-wing DNA-binding motifs. lambda-Terminase with the recognition helix of 21 preferentially packages 21 DNA. This chimeric terminase's ability to package lambdaDNA is reduced approximately 20-fold. Phage lambda with the chimeric terminase is...

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Identifiers

PMID: 19841094
DOI: 10.1534/genetics.109.108548
PMCID: PMC2815929

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Source receipt: pubmed, retrieved 7 Sept 2026.

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