Article
Aberrant concentrations of liver-derived plasma albumin mRNA in liver pathologies.
Clinical chemistry - 1 Jan 2010
Chan Rebecca W Y, Wong John, Chan Henry L Y, Mok Tony S K, Lo Wyatt Y W, Lee Vincent, To Ka F, Lai Paul B S, Rainer Timothy H, Lo Y M Dennis, Chiu Rossa W K
Abstract excerpt
BACKGROUND: We hypothesized that liver-derived mRNA, such as ALB (albumin) mRNA, would be released into human plasma with liver cell death. METHODS: We genotyped ALB mRNA molecules in samples of plasma and whole blood from liver and bone marrow transplant recipients by RNA single-nucleotide polymorphism analysis. Plasma and whole blood ALB mRNA genotypes were compared with the DNA genotypes of the recipients and...
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