Article
Effect of lethality on the extinction and on the error threshold of quasispecies.
Journal of theoretical biology - 21 Feb 2010
Tejero Hector, Marín Arturo, Montero Francisco
Abstract excerpt
In this paper the effect of lethality on error threshold and extinction has been studied in a population of error-prone self-replicating molecules. For given lethality and a simple fitness landscape, three dynamic regimes can be obtained: quasispecies, error catastrophe, and extinction. Using a simple model in which molecules are classified as master, lethal and non-lethal mutants, it is possible to obtain the...
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