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Article

The Imd pathway is involved in antiviral immune responses in Drosophila.

PloS one - 15 Oct 2009

Costa Alexandre, Jan Eric, Sarnow Peter, Schneider David

Abstract excerpt

Cricket Paralysis virus (CrPV) is a member of the Dicistroviridae family of RNA viruses, which infect a broad range of insect hosts, including the fruit fly Drosophila melanogaster. Drosophila has emerged as an effective system for studying innate immunity because of its powerful genetic techniques and the high degree of gene and pathway conservation. Intra-abdominal injection of CrPV into adult flies causes a...

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Identifiers

PMID: 19829691
DOI: 10.1371/journal.pone.0007436
PMCID: PMC2758544

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