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Article

Valosin containing protein associated inclusion body myopathy: abnormal vacuolization, autophagy and cell fusion in myoblasts.

Neuromuscular disorders : NMD - 1 Nov 2009

Vesa Jouni, Su Hailing, Watts Giles D, Krause Sabine, Walter Maggie C, Martin Barbara, Smith Charles, Wallace Douglas C, Kimonis Virginia E

Abstract excerpt

Inclusion body myopathy associated with Paget's disease and frontotemporal dementia (IBMPFD) is caused by mutations in the valosin containing protein (VCP) gene. The disease is associated with progressive proximal muscle weakness, inclusions and vacuoles in muscle fibers, malfunction in the bone remodeling process resulting in Paget's disease, and premature frontotemporal dementia. VCP is involved in several...

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Source

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Identifiers

PMID: 19828315
DOI: 10.1016/j.nmd.2009.08.003
PMCID: PMC2782446

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Valosin containing protein associated inclusion body myopathy: abnormal vacuolization, autophagy and cell fusion in myoblasts.PMID 19828315Read ↗

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