Article
Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis.
Journal of neuroimmunology - 30 Nov 2009
Zarif Yeganeh M, Ghaffarpour M, Farhud D D, Karimlou M, Ghabaee M, Haghighi Nazari A, Najmabadi H, Ohadi M
Abstract excerpt
Caveolin 1 (CAV1) is a component of the myelin sheath and the expression of the gene encoding this protein is increased during myelination in Schwann cells and oligodendrocytes. We sought to investigate the homozygote haplotype compartment in a recently identified polymorphic purine complex at the upstream region of the human CAV1 gene in multiple sclerosis (MS). In a case/control study design, the region was...
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