Article
Association between the ACCN1 gene and multiple sclerosis in Central East Sardinia.
PloS one - 30 May 2007
Bernardinelli Luisa, Murgia Salvatore Bruno, Bitti Pier Paolo, Foco Luisa, Ferrai Raffaela, Musu Luigina, Prokopenko Inga, Pastorino Roberta, Saddi Valeria, Ticca Anna, Piras Maria Luisa, Cox David Roxbee, Berzuini Carlo
Abstract excerpt
Multiple genome screens have been performed to identify regions in linkage or association with Multiple Sclerosis (MS, OMIM 126200), but little overlap has been found among them. This may be, in part, due to a low statistical power to detect small genetic effects and to genetic heterogeneity within and among the studied populations. Motivated by these considerations, we studied a very special population, namely...
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