Current approaches to the genetics of coronary heart disease (CHD) including an account of work done at Hammersmith Hospital.

Article

Current approaches to the genetics of coronary heart disease (CHD) including an account of work done at Hammersmith Hospital.

Bollettino della Societa italiana di biologia sperimentale - 1 Nov 1990

Myant N B

Abstract excerpt

Genetic variability makes a significant contribution to CHD in Western populations. The major genetic component in CHD in the general population is polygenic; only a small fraction of the total genetic contribution is due to rare monogenic disorders such as FH. Two approaches to the investigation of the genetics of CHD are described. In the first, the frequencies of the alleles at polymorphic sites in the apoB...

Topics

Apolipoproteins B
Coronary Disease
Europe
Gene Frequency
Genetic Predisposition to Disease
Genetic Testing
Hospitals
Humans
Hyperlipoproteinemia Type II
Lipoproteins, LDL
London

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

United States

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