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Gene profiling, biomarkers and pathways characterizing HCV-related hepatocellular carcinoma

12 Oct 2009

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) worldwide. The molecular mechanisms of HCV-induced hepatocarcinogenesis are not yet fully elucidated. Besides indirect effects as tissue inflammation and regeneration, a more direct oncogenic activity of HCV can be postulated leading to an altered expression of cellular genes by early HCV viral proteins. In the...

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PMID: 19821982
DOI: 10.1186/1479-5876-7-85

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