Article
Genetic basis of beta-cell dysfunction in man.
Diabetes, obesity & metabolism - 1 Nov 2009
Groop L, Lyssenko V
Abstract excerpt
Although the genetic causes of monogenic disorders have been successfully identified in the past, the success in dissecting the genetics of complex polygenic diseases has until now been limited. With the introduction of whole genome wide association studies (WGAS) in 2007, the picture has been dramatically changed. Today we know of about 20 genetic variants increasing the risk of type 2 diabetes (T2D). Most of...
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