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Article

Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68.

PLoS pathogens - 1 Oct 2009

E Xiaofei, Hwang Seungmin, Oh Soohwan, Lee Jong-Soo, Jeong Joseph H, Gwack Yousang, Kowalik Timothy F, Sun Ren, Jung Jae U, Liang Chengyu

Abstract excerpt

Gamma-herpesviruses (gammaHVs) have developed an interaction with their hosts wherein they establish a life-long persistent infection and are associated with the onset of various malignancies. One critical virulence factor involved in the persistency of murine gamma-herpesvirus 68 (gammaHV68) is the viral homolog of the Bcl-2 protein (vBcl-2), which has been implicated to counteract both host apoptotic responses...

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Identifiers

PMID: 19816569
DOI: 10.1371/journal.ppat.1000609
PMCID: PMC2752191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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