Article
Lack of association of three common polymorphisms in toll-like receptors (TLRs), TLR2+597T>C, +1350C>T and Arg753Gln with cancer risk: a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Yang Xin, Wang Xiao-Xiao, Qiu Man-Tang, Hu Jing-Wen, Yin Rong, Xu Lin, Zhang Qin
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) occurring in Toll-like receptors (TLRs) may contribute to cancer risk. Many polymorphisms of TLR2 have been studied for associations, but the findings are conflicting. METHODOLOGY/PRINCIPAL FINDINGS: We performed a meta-analysis of 14 studies to confirm the association between TLR2+597T>C (rs3804099), +1350C>T (rs3804100) and Arg753Gln (rs5743708) polymorphisms...
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