Article
Selective growth inhibition of cancer cells by L-methioninase-containing fusion protein targeted to the urokinase receptor.
Pharmacology - 1 Jan 2009
Palwai Naveen R, Zang Xiao-Ping, Harrison Roger G, Benbrook Doris, Pento J Thomas
Abstract excerpt
BACKGROUND: We have reported the development of a novel fusion protein (FP) consisting of an amino-terminal fragment of urokinase linked to the amino terminus of the enzyme L-methioninase (L-M). The present study compared the effect of this novel FP on the proliferation of human ovarian, skin, br...
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