Article
Bergerac strains of Caenorhabditis elegans revisited: expansion of Tc1 elements imposes a significant genomic and fitness cost.
G3 (Bethesda, Md.) - 4 Nov 2022
Daigle Austin T, Deiss Thaddeus C, Melde Robert H, Bergthorsson Ulfar, Katju Vaishali
Abstract excerpt
The DNA transposon Tc1 was the first transposable element to be characterized in Caenorhabditis elegans and to date, remains the best-studied transposable element in Caenorhabditis worms. While Tc1 copy-number is regulated at approximately 30 copies in the laboratory Bristol N2 and the vast majority of C. elegans strains, the Bergerac strain and its derivatives have experienced a marked Tc1 proliferation. Given...
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