Article
Efficient maximum likelihood pedigree reconstruction.
Theoretical population biology - 1 Dec 2009
Cowell Robert G
Abstract excerpt
A simple and efficient algorithm is presented for finding a maximum likelihood pedigree using microsatellite (STR) genotype information on a complete sample of related individuals. The computational complexity of the algorithm is at worst (O(n(3)2(n))), where n is the number of individuals. Thus it is possible to exhaustively search the space of all pedigrees of up to thirty individuals for one that maximizes the...
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