Chromosome territories, X;Y translocation and Premature Ovarian Failure: is there a relationship?

doi:10.1186/1755-8166-2-19

Article

Chromosome territories, X;Y translocation and Premature Ovarian Failure: is there a relationship?

27 Sept 2009

Abstract excerpt

BACKGROUND: Premature ovarian failure (POF) is a secondary hypergonadotrophic amenorrhea occurring before the age of 40 and affecting 1-3% of females. Chromosome anomalies account for 6-8% of POF cases, but only few cases are associated with translocations involving X and Y chromosomes.This study shows the cytogenetic and molecular analysis of a POF patient came to our attention as she developed a left ovary...

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