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Cytogenetic analyses of premature ovarian failure using karyotyping and interphase fluorescence <i>in situ</i> hybridization (FISH) in a group of 1000 patients

2 Dec 2009

Abstract excerpt

To evaluate the implication of chromosome abnormalities in the etiology of premature ovarian failure (POF), 1000 patients with POF recruited at the Department of Cytogenetics of Farhat Hached Hospital (Sousse, Tunisia) between January 1996 and December 2008. Chromosome analyses were performed by using karyotyping and interphase fluorescent in situ hybridisation (FISH) using a centromeric probe of the chromosome X...

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PMID: 20345472
DOI: 10.1111/j.1399-0004.2009.01359.x

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