Article
Cytogenetic analysis of 531 Chinese women with premature ovarian failure.
Human reproduction (Oxford, England) - 1 Jul 2012
Jiao Xue, Qin Chunrong, Li Jie, Qin Yingying, Gao Xuan, Zhang Bo, Zhen Xiumei, Feng Yun, Simpson Joe Leigh, Chen Zi-jiang
Abstract excerpt
BACKGROUND: This retrospective cohort study was to determine the frequency and types of chromosomal abnormalities in Han Chinese women with well-documented premature ovarian failure (POF). METHODS: Karyotype analysis and correlation to phenotypes were performed on 531 Chinese patients with proven POF (FSH > 40 mIU/ml) attending four reproductive centers in China. G-banded metaphase chromosomes were prepared and...
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