Article
Anthracycline dose intensification in acute myeloid leukemia.
The New England journal of medicine - 24 Sept 2009
Fernandez Hugo F, Sun Zhuoxin, Yao Xiaopan, Litzow Mark R, Luger Selina M, Paietta Elisabeth M, Racevskis Janis, Dewald Gordon W, Ketterling Rhett P, Bennett John M, Rowe Jacob M, Lazarus Hillard M, Tallman Martin S
Abstract excerpt
BACKGROUND: In young adults with acute myeloid leukemia (AML), intensification of the anthracycline dose during induction therapy has improved the rate of complete remission but not of overall survival. We evaluated the use of cytarabine plus either standard-dose or high-dose daunorubicin as induction therapy, followed by intensive consolidation therapy, in inducing complete remission to improve overall survival....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.