Article
Impact of sodium/proton exchanger 3 gene variants on sudden infant death syndrome.
The Journal of pediatrics - 1 Jan 2010
Poetsch Micaela, Nottebaum Bente J, Wingenfeld Lisa, Frede Stilla, Vennemann Mechtild, Bajanowski Thomas
Abstract excerpt
OBJECTIVE: To determine the contribution of variations in the sodium/proton exchanger 3 (NHE3) gene in sudden infant death syndrome (SIDS). STUDY DESIGN: Variations in the exons and promoter of the NHE3 gene were analyzed with direct sequencing analysis and mini sequencing (SNaPshot analysis) in 251 cases of SIDS, plus 50 infant control subjects who had died of other causes, and 170 healthy adults. RESULTS: The...
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