Article
Connective tissue disease in southeast Georgia. A community based study of immunogenetic markers and autoantibodies.
The Journal of rheumatology - 1 Aug 1990
Arnett F C, Bias W B, McLean R H, Engel M, Duvic M, Goldstein R, Freni-Titulaer L, McKinley T W, Hochberg M C
Abstract excerpt
HLA antigens, C4 allotypes and T cell antigen receptor (TcR)beta DNA polymorphisms were determined in a community based study of connective tissue diseases (CTD). HLA-B8, DR3 and C4A null phenotypes occurred frequently in Caucasian patients with CTD, especially those with systemic lupus erythemat...
Topics
- Alleles
- Antibodies, Antinuclear
- Autoantibodies
- Case-Control Studies
- Complement C4
- Genetic Markers
- Georgia
- HLA Antigens
- Humans
- Immunoglobulin Allotypes
- Lupus Erythematosus, Systemic
- Myositis
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell
- Scleroderma, Systemic