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Article

Human RAP1 inhibits non‐homologous end joining at telomeres

17 Sept 2009

Abstract excerpt

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Topics

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Share to DNA Repair Mechanisms
Share to RNA modifications and cancer
Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19763083
DOI: 10.1038/emboj.2009.275

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human RAP1 inhibits non‐homologous end joining at telomeresPMID 19763083Read ↗

A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA EndsSemantic proximity Read ↗

Human RAP1 specifically protects telomeres of senescent cells from DNA damageSemantic proximity Read ↗

TALEN Gene Knockouts Reveal No Requirement for the Conserved Human Shelterin Protein Rap1 in Telomere Protection and Length RegulationSemantic proximity Read ↗

TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusionsSemantic proximity Read ↗

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes endSemantic proximity Read ↗

TDP1 is required for efficient non-homologous end joining in human cellsSemantic proximity Read ↗

TRF2 Protects Human Telomeres from End-to-End FusionsSemantic proximity Read ↗

Chromosome end protection by RAP1-mediated inhibition of DNA-PKSemantic proximity Read ↗

Human POT1 Facilitates Telomere Elongation by TelomeraseSemantic proximity Read ↗

A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.Semantic proximity Read ↗

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of TelomeresSemantic proximity Read ↗

Human Rap1 Interacts Directly with Telomeric DNA and Regulates TRF2 Localization at the TelomereSemantic proximity Read ↗

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