Article
Predicting response to short-acting bronchodilator medication using Bayesian networks.
Pharmacogenomics - 1 Sept 2009
Himes Blanca E, Wu Ann Chen, Duan Qing Ling, Klanderman Barbara, Litonjua Augusto A, Tantisira Kelan, Ramoni Marco F, Weiss Scott T
Abstract excerpt
AIMS: Bronchodilator response tests measure the effect of beta(2)-agonists, the most commonly used short-acting reliever drugs for asthma. We sought to relate candidate gene SNP data with bronchodilator response and measure the predictive accuracy of a model constructed with genetic variants. MATERIALS & METHODS: Bayesian networks, multivariate models that are able to account for simultaneous associations and...
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