Article
Novel mutations in the calreticulin gene core promoter and coding sequence in schizoaffective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Olad Nabi M, Mirabzadeh A, Feizzadeh G, Khorram Khorshid H R, Karimlou M, Zarif Yeganeh M, Asgharian A M, Najmabadi H, Ohadi M
Abstract excerpt
We have recently reported the first case of mutation in the core promoter sequence of the human calreticulin gene in a family case of schizoaffective disorder. Remarkably, this gene coincides with a region of suggested linkage at 19p13.2, identified in a whole genome scan [Hamshere et al. (2005); Arch Gen Psychiatry 62;1081-1088]. The identified mutation was located at the conserved position -48 from the...
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