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Article

Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects

16 Sept 2009

Abstract excerpt

BACKGROUND: Although much progress has been made on antipsychotic drug development, precise mechanisms behind the action of typical and atypical antipsychotics are poorly understood. METHODS: We performed genome-wide expression profiling to study effects of typical antipsychotics and atypical antipsychotics in the postmortem liver of schizophrenia patients using microarrays (Affymetrix U133 plus2.0). We...

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PMID: 19758435
DOI: 10.1186/1471-244x-9-57

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