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Article

Calcipotriol induces apoptosis in psoriatic keratinocytes

15 Sept 2009

Abstract excerpt

In recent years, vitamin D3 analogues have become one of the most widely prescribed topical treatments for mild or moderate chronic plaque psoriasis. These molecules are effective and safe, but their exact mechanism of action is not completely understood. In vitro studies have shown that D3 analogues decrease proliferation and induce differentiation of keratinocytes, and have strong immunomodulating effects, but...

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PMID: 19758385
DOI: 10.1111/j.1365-2230.2009.03518.x

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