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Article

Reproducibility of Serologic Assays for Influenza Virus A (H5N1)

1 Aug 2009

Abstract excerpt

Hemagglutination-inhibition (HI) and neutralization are used to evaluate vaccines against influenza virus A (H5N1); however, poor standardization leads to interlaboratory variation of results. A candidate antibody standard (07/150) was prepared from pooled plasma of persons given clade 1 A/Vietnam/1194/2004 vaccine. To test human and sheep antiserum, 15 laboratories used HI and neutralization and reassortant...

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PMID: 19751587
DOI: 10.3201/eid1508.081754

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