Article
Cross-protectiveness and immunogenicity of influenza A/Duck/Singapore/3/97(H5) vaccines against infection with A/Vietnam/1203/04(H5N1) virus in ferrets.
The Journal of infectious diseases - 15 Oct 2006
Lipatov Aleksandr S, Hoffmann Erich, Salomon Rachelle, Yen Hui-Ling, Webster Robert G
Abstract excerpt
Ferrets were immunized with two 7- mu g doses of hemagglutinin from inactivated whole-virus vaccines containing the hemagglutinin gene of A/Duck/Singapore/3/97(H5N3) then inoculated with a lethal dose of A/Vietnam/1203/04(H5N1) (Viet/1203/04). Serum samples did not react with Viet/1203/04 in hemagglutination-inhibition (HI) or virus-neutralization (VN) tests. All vaccinated ferrets survived the challenge, whereas...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
