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Article

Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways.

Bioinformatics (Oxford, England) - 15 Nov 2009

Sadreyev Ruslan I, Feramisco Jamison D, Tsao Hensin, Grishin Nick V

Abstract excerpt

MOTIVATION: Systematic analysis of connection between proteins, their cellular function and phenotypic manifestations in disease is a central problem of biological and clinical research. The solution to this problem requires the development of new approaches to link the rapidly growing dataset of gene-disease associations with the many complex and overlapping phenotypes of human disease. RESULTS: We analyze...

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Identifiers

PMID: 19744994
DOI: 10.1093/bioinformatics/btp538
PMCID: PMC2773259

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