Article
An escalating dose regimen of pegylated interferon and ribavirin in HCV cirrhotic patients referred for liver transplant.
Transplantation - 15 Sept 2009
Massoumi Hatef, Elsiesy Hussein, Khaitova Viktoriya, Peterson Brent, Norkus Edward, Grewal Priya, Liu Lawrence, Chang Charissa, Bach Nancy, Schiano Thomas D
Abstract excerpt
BACKGROUND: To lessen the severity of recurrent hepatitis C virus (HCV) postliver transplantation (post-LT) by treating HCV patients with cirrhosis, we assessed the safety and efficacy of an escalating dose pegylated interferon (PEG-IFN)/ribavirin protocol in pre-LT patients. METHODS: Ninety patients were treated with 90 microg PEG-IFN alpha-2a and 400 mg ribavirin and advanced to 180 microg and 800 to 1200 mg,...
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