Article
Micro-computed tomography measurements of peripheral lung pathology in chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society - 15 Sept 2009
Hogg James C, McDonough John E, Sanchez Pablo G, Cooper Joel D, Coxson Harvey O, Elliott William M, Naiman David, Pochettino Marcus, Horng Debra, Gefter Warren B, Wright Alex C
Abstract excerpt
BACKGROUND: The smaller airways, < 2 mm in diameter, offer little resistance in normal lungs, but become the major site of obstruction in chronic obstructive pulmonary disease (COPD). OBJECTIVE: To examine bronchiolar remodeling and alveolar destruction in COPD using micro-computed tomography (micro-CT). METHODS: Micro-CT was used to measure the number and cross-sectional lumen area of terminal bronchioles (TB)...
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