Article
Genetic link between cancer and thrombosis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Oct 2009
Boccaccio Carla, Comoglio Paolo M
Abstract excerpt
From the beginning of their lives, cancer cells exert a procoagulant activity in their microenvironment, which can extend systemically and become clinically evident as Trousseau's syndrome, the well-known association between tumor and thrombosis. It is becoming clear that the genetic mechanisms responsible for neoplastic transformation (activation of oncogenes such as RAS or MET, and inactivation of tumor...
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