Article
Single cell coagulomes as constituents of the oncogene-driven coagulant phenotype in brain tumours.
Thrombosis research - 1 Apr 2018
Tawil Nadim, Chennakrishnaiah Shilpa, Bassawon Rayhaan, Johnson Radia, D'Asti Esterina, Rak Janusz
Abstract excerpt
Molecular profiling of human cancers revealed a startling diversity in disease-causing mechanisms superseding histological and anatomical commonalities. The emerging molecular subtypes and disease entities are often driven by distinct oncogenic pathways and their effectors, including those acting extracellularly on the vascular and coagulation systems. Indeed, several oncogenic mutations such as those affecting...
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