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Article

Genetic and environmental influences on pro-inflammatory monocytes in bipolar disorder: a twin study.

Archives of general psychiatry - 1 Sept 2009

Padmos Roos C, Van Baal G Caroline M, Vonk Ronald, Wijkhuijs Annemarie J M, Kahn René S, Nolen Willem A, Drexhage Hemmo A

Abstract excerpt

CONTEXT: A monocyte pro-inflammatory state has previously been reported in bipolar disorder (BD). OBJECTIVE: To determine the contribution of genetic and environmental influences on the association between monocyte pro-inflammatory state and BD. DESIGN: A quantitative polymerase chain reaction case-control study of monocytes in bipolar twins. Determination of the influence of additive genetic, common, and unique...

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PMID: 19736352
DOI: 10.1001/archgenpsychiatry.2009.116

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