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Article

Is thrombophilia associated with placenta-mediated pregnancy complications? A prospective cohort study.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2014

Rodger M A, Walker M C, Smith G N, Wells P S, Ramsay T, Langlois N J, Carson N, Carrier M, Rennicks White R, Shachkina S, Wen S W

Abstract excerpt

BACKGROUND: Case control studies suggest that genetic thrombophilias increase the risk of placenta-mediated pregnancy complications (pregnancy loss, small for gestational age (SGA), preeclampsia and/or placental abruption). Cohort studies have not supported this association but were underpowered to detect small effects. OBJECTIVE: To determine if factor V Leiden (FVL) or the prothrombin gene mutation (PGM) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24447367
DOI: 10.1111/jth.12509

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