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Article

Anomalous electrophoretic migration of newly synthesized ribosomal RNAs and their precursors from cells with DKC1 mutations.

FEBS letters - 17 Sept 2009

Gu Bai-Wei, Zhao Chunjun, Fan Jian-Meng, Dai Qing, Bessler Monica, Mason Philip J

Abstract excerpt

Mutations in the X-linked gene, DKC1, encoding dyskerin, cause dyskeratosis congenita by leading to decreased telomerase activity and causing short telomeres. Dyskerin is also a pseudouridine synthase that modifies nascent ribosomal and other RNAs and it is not known if this function is affected...

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Source

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Identifiers

PMID: 19729012
DOI: 10.1016/j.febslet.2009.08.038
PMCID: PMC2745346

Genes

DKC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19729012-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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