Article
Immunophenotypic and cell cycle analysis of lymph node cells from dimethylbenzanthracene-treated mice.
Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1990
Halliday G M, Cavanagh L L, Muller H K
Abstract excerpt
The chemical carcinogen 7, 12-dimethylbenz-(a)anthracene (DMBA) depletes Langerhans cells from murine epidermis. Application of contact sensitizers to DMBA-treated skin induces specific immunological tolerance due to a DMBA-resistant epidermal antigen presenting cell (APC) migrating to local lymp...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Administration, Cutaneous
- Animals
- Antigens, Differentiation
- B-Lymphocytes
- Cell Count
- Cell Cycle
- Immune Tolerance
- Lymph Nodes
- Mice
- Mice, Inbred BALB C
- Phenotype
- T-Lymphocytes