Article
Comparison and significance of specific and non-specific cellular immunity in patients with chronic hepatitis B caused by infection with genotypes B or C of hepatitis B virus.
Science in China. Series C, Life sciences - 1 Aug 2009
Gu XiBing, Yang XiaoJuan, Wang Dong, Hua Zhong, Wu HangYuan, Chen HaoKun, Xu YueQin, Lu ZhongHua
Abstract excerpt
The present study was designed to investigate possible relationships between the genotypes of hepatitis B virus (HBV) and the HBV-specific cytotoxic T lymphocyte (CTL) responses. HBV genotypes, HBV specific CTL HBV DNA and other markers of HBV infection were determined in 138 patients with chronic hepatitis B. The results showed that the patients infected with genotype C (n=62) had a significantly lower...
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