Article
Apoptotic engulfment pathway and schizophrenia.
PloS one - 1 Sept 2009
Chen Xiangning, Sun Cuie, Chen Qi, O'Neill F Anthony, Walsh Dermot, Fanous Ayman H, Chowdari Kodavali V, Nimgaonkar Vishwajit L, Scott Adrian, Schwab Sibylle G, Wildenauer Dieter B, Che Ronglin, Tang Wei, Shi Yongyong, He Lin, Luo Xiong-Jian, Su Bing, Edwards Todd L, Zhao Zhongming, Kendler Kenneth S
Abstract excerpt
BACKGROUND: Apoptosis has been speculated to be involved in schizophrenia. In a previously study, we reported the association of the MEGF10 gene with the disease. In this study, we followed the apoptotic engulfment pathway involving the MEGF10, GULP1, ABCA1 and ABCA7 genes and tested their association with the disease. METHODOLOGY/PRINCIPAL FINDINGS: Ten, eleven and five SNPs were genotyped in the GULP1, ABCA1...
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