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Article

The VEGF-induced transcriptional response comprises gene clusters at the crossroad of angiogenesis and inflammation

1 Jan 2009

Abstract excerpt

VEGF-A is the major trigger of vasculogenesis and physiologic angiogenesis. We have investigated to which extent the gene repertoire induced by VEGF-A in endothelial cells is distinct from that of other growth factors and inflammatory cytokines. Genes upregulated in human umbilical vein endothelial cells treated with VEGF, EGF or IL-1 were compared by microarray analysis and clusters characteristic for individual...

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PMID: 19718476
DOI: 10.1160/th08-12-0830

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