Article
An autophagy gene, MgATG5, is required for cell differentiation and pathogenesis in Magnaporthe oryzae.
Current genetics - 1 Aug 2009
Lu Jian-Ping, Liu Xiao-Hong, Feng Xiao-Xiao, Min Hang, Lin Fu-Cheng
Abstract excerpt
Autophagy is a conserved degradation pathway that is involved in the maintenance of normal cell differentiation and development. The Saccharomyces cerevisiae ATG5 gene is an important component of the autophagy process. In this study, we identified MgATG5 as an autophagy-related gene in Magnaporthe oryzae that is homologous to ATG5. Using targeted gene replacement, an Mgatg5Delta mutant was generated and fungal...
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