Article
Genetic structure of Plasmodium vivax isolates from two malaria endemic areas in Afghanistan.
Acta tropica - 1 Jan 2010
Zakeri Sedigheh, Safi Najibullah, Afsharpad Mandana, Butt Waqar, Ghasemi Faezeh, Mehrizi Akram Abouie, Atta Hoda, Zamani Ghasem, Djadid Navid Dinparast
Abstract excerpt
In this study, the nature and extent of genetic diversity of Plasmodium vivax populations circulating in Afghanistan have been investigated by analyzing three genetic markers: csp, msp-1, and msp-3 alpha. Blood samples (n=202) were collected from patients presenting with vivax malaria from south-western (Herat) and south-eastern (Nangarhar) parts of Afghanistan, and analysed using nested-PCR/RFLP and sequencing...
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